A group of college students book a bargain dream holiday to a remote tropical island, little knowing that they have been lured there by the island's evil owner to fulfill an ancient voodoo prophecy. Soon, what appears to be paradise is transformed as friends and siblings are pitched against each other in a desperate fight for survival. Doubt, suspicion and panic splinter the group as each member begins to fall victim to the terrifying reality of their own worst nightmares. Can those who are left find the strength to confront and overcome the fear that will otherwise be their end, or will the voodoo curse win out?

When the motorcyclist Johnny Blaze finds that his father Barton Blaze has a terminal cancer, he accepts a pact with the Mephistopheles, giving his soul for the health of his beloved father. But the devil deceives him, and Barton dies in a motorcycle accident during an exhibition. Johnny leaves the carnival, his town, his friends and his girlfriend Roxanne. Years later Johnny Blaze becomes a famous motorcyclist, who risks his life in his shows, and he meets Roxanne again, now a TV reporter. However, Mephistopheles proposes Johnny to release his contract if he become the "Ghost Rider" and defeat his evil son Blackheart, who wants to possess one thousand evil souls and transform hell on earth.